The Direzione Centrale per i Servizi Antidroga is a multiagency body of the Department of Public Security under the direction of the Chief of Police –Director General of Public Security. It implements the guidelines issued by the Minister of the Interior in the areas of coordination of law enforcement agencies, planning and management of the law enforcement services with the aim of  preventing and combating illicit traffic in drugs and psychotropic substances.

The organization of the Direzione Centrale is regulated by the Interministerial Decree of 15 June 1991. Its staff is composed of an equal number of law enforcement officers from the State Police, the Carabinieri and the Guardia di Finanza as well as civilian personnel of the Ministry of the Interior.  The Director is a top-ranking officer from one of  the three Italian law enforcement agencies and changes every three years on a rotation basis. In particular, the Direzione Centrale per i Servizi Antidroga, coordinates the info-operational activities of the law enforcement agencies involved in the fight against national and international drug trafficking, promoting new strategies and agreements with foreign counterparts through the Law Enforcement Attachés of the Direzione Centrale per i Servizi Antidroga posted to the sensitive areas and providing training to drug producing and transit countries.